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Some patients taking weight-loss drugs, including popular GLP-1 treatments, reported reducing their consumption of alcohol, according to a new study published recently in the scientific journal JAMA Network Open.
The study surveyed around 14,000 members of the weight-loss program WeightWatchers (WW-6.73%) who were taking medications like Wegovy, Mounjaro, or older drugs such as metformin. About 45% of those who drank alcohol reported drinking less after starting their anti-obesity medication. Additionally, people with severe obesity and heavy drinkers were the ones most likely to cut back.
Wegovy and Mounrjaro belong to the class of drugs known as GLP-1 medications, made popular by Novo Nordisk's diabetes treatment Ozempic. These drugs mimic a hormone that regulates appetite and blood sugar and have become highly sought after as treatments for obesity and Type 2 diabetes.
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This new study follows other anecdotal evidence from patients and healthcare providers that suggests GLP-1 drugs can help users curb addictions.
Previous studies have also found that GLP-1 medications could help people with substance use disorders. And a Morgan Stanley (MS-0.30%) survey from earlier this year found that people using GLP-1 drugs -- among them Ozempic, Wegovy, Mounjaro, and Zepbound -- reduced their consumption of alcohol.
The investment bank surveyed approximately 300 GLP-1 users about their consumption habits while taking the medication. About 56-62% of alcohol consumers on GLP-1s reported drinking less alcohol since starting the medications, with about 14-18% cutting their alcohol consumption entirely.
The analysts noted they were "cautious about drawing conclusions" from their survey about the impact of GLP-1 drugs on addictive behaviors. While research hasn't yet proven a causal link, clinical trials are currently underway to better understand the effects of GLP-1s on alcohol and tobacco consumption.
One small trial found that people with alcohol use disorder drank less after taking semaglutide -- the active ingredient in Novo Nordisk's Ozempic -- compared with people who took a placebo.