One in four pregnancies end in miscarriage, according to the World Health Organization. But while there are cultural scripts for responding to pregnancy and birth, there isn't one for miscarriage. Instead, families facing pregnancy loss often experience shame, stigma and isolation.

Amanda Knox wants to change that.

Knox, who in 2015 was exonerated by Italy's highest court after being wrongfully convicted of murder, is now an independent journalist and podcaster who co-hosts the podcast "Labyrinths: Getting Lost with Amanda Knox" with her husband, Christopher Robinson.

When Knox had a miscarriage during the COVID-19 pandemic, she made infertility the focus of a new season of "Labyrinths."

Her experience with miscarriage was isolating, she said, and brought up questions "reminiscent ... of my own wrongful conviction experience," she said. Questions like, "Why is this happening to me? It's so unfair. It doesn't make any sense," she said. "And I felt very alone. I had never talked to anyone before about miscarriage experiences."