Lucy Letby's legal team is set to reveal fresh evidence that "significantly undermines" her convictions, her barrister said in a statement released on Saturday.
The neonatal nurse is serving life imprisonment for the murders of seven infants and the attempted murders of seven others at the Countess of Chester Hospital between 2015 and 2016.
But since the convictions, dozens of statisticians, scientists, doctors and nurses have come forward to challenge the evidence presented to the jury.
Mark McDonald, Letby's new barrister, has issued a press notice announcing that the team will disclose "fresh developments on the case" on Monday afternoon.
"At the conference we will also be announcing new evidence which significantly undermines the convictions," the press notice added.
The team has not released further details about the new evidence.
Since the trial, it was revealed that door-swipe data used to place various doctors and nurses at the scene of baby collapses and deaths was flawed.
The jury was also not told about several internal and external reviews carried out by the Countess of Chester, public bodies, outside medical experts and pathologists that failed to find any evidence of foul play.
Nor did jurors hear that the neonatal unit had suffered an outbreak of the deadly bug pseudomonas and had been criticised for being crowded and understaffed, with consultants making only two ward rounds per week.
Letby, 34, of Hereford, is already serving 15 whole-life terms, but following the verdicts, Cheshire Constabulary said it would be reviewing about 4,000 more babies for whom she cared at the Countess of Chester and Liverpool Women's Hospital, where she completed placements in 2012 and 2015.
Earlier this month, Cheshire Constabulary confirmed it had questioned Letby about more deaths and collapses at both hospitals.
Mr McDonald, who is planning to take Letby's case to the Criminal Cases Review Commission, said the former nurse had voluntarily agreed to the interview, had not been arrested and maintained her innocence.
The barrister said he recently met with more than 50 experts in neonatology, pathology and statistics who were willing to question the evidence against her.
Mr McDonald said there would be "a line" of experts should police bring further charges.
The prosecution says Letby was convicted on a multitude of evidence from specialists, and that the defence could have called rebuttal witnesses but chose not to.
If Letby is tried for new crimes, the prosecution will need to find a new medical expert.
Dewi Evans, a retired paediatrician from Carmarthen who was the lead medical expert against Letby in the first trial, has already said he would not take the stand for any future trials.