Back in May, a study was published
suggesting that popular weight-loss drugs such as Ozempic and wegovy could
curb alcohol cravings by as much as 70%. At the time, researchers weren't
entirely sure why the GLP-1s had such a profound effect on alcohol
receptors, but that may have all changed.
A new study published Wednesday in the journal
Scientific Reports
found that GLP-1s slow the absorption of alcohol into the bloodstream, thus
minimizing its effects on the brain. it's not entirely different from what
GLP-1s do with food, which is to resemble the GLP-1 hormone and effectively
slow digestion.
GLP-1s,or glucagon-like peptide-1 receptor agonists,are a class of
medications originally developed to treat Type 2 Diabetes. Thay work by
mimicking the effects of the naturally occurring GLP-1 hormone, which
regulates blood sugar levels. This mimicking action extends to slowing
gastric emptying, meaning food and liquids, including alcohol, remain in the
stomach longer.
the study involved administering alcohol to rats both with and without GLP-1
treatment. Researchers observed that the rats treated with GLP-1s exhibited
considerably lower blood alcohol concentrations compared to the control
group. This suggests that the medications physically delay the rate at which
alcohol enters the bloodstream.